CDC25C anticorps
Aperçu rapide pour CDC25C anticorps (ABIN2855486)
Antigène
Voir toutes CDC25C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to CDC25C (cell division cycle 25 homolog C (S. pombe))
CDC25C antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human CDC25C. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: A431 , HeLa
Validation: KO/KD, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.63 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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Autre désignation
- cell division cycle 25C
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Sujet
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This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Cellular Localization: Nucleus -
Poids moléculaire
- 53 kDa
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ID gène
- 995
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UniProt
- P30307
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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