Kallikrein 6 anticorps

N° du produit ABIN2855841

Cet anticorps anti-Kallikrein 6 est un anticorps Lapin Polyclonal détectant Kallikrein 6 dans ICC et IF. Adapté pour Humain.

Aperçu rapide pour Kallikrein 6 anticorps (ABIN2855841)

Antigène: Kallikrein 6 (KLK6)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 6 est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-Kallikrein 6 anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Kallikrein 6 (kallikrein-related peptidase 6)
Kallikrein 6 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.88 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Kallikrein 6

Antigène: Kallikrein 6 (KLK6)

Autre désignation: kallikrein related peptidase 6

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Cellular Localization: Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome

Poids moléculaire: 27 kDa

ID gène: 5653

UniProt: Q92876

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling