ENPP2 anticorps (C-Term)

N° du produit ABIN2856278

Détail du produit anti-ENPP2 anticorps

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENPP2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to Autotaxin (ectonucleotide pyrophosphatase/phosphodiesterase 2)
Autotaxin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human Autotaxin. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.13 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ENPP2 (ABIN2856278)

Tsukahara, Haniu, Uemura, Matsuda: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." dans: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).

Détails sur ENPP2

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Autre désignation: ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2 Produits)

Synonymes: anticorps ATX, anticorps ATX-X, anticorps AUTOTAXIN, anticorps LysoPLD, anticorps NPP2, anticorps PD-IALPHA, anticorps PDNP2, anticorps Npps2, anticorps PD-Ialpha, anticorps Pdnp2, anticorps MGC132047, anticorps atx, anticorps zgc:63550, anticorps autotaxin, anticorps enpp2, anticorps enpp2a, anticorps enpp2b, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog, anticorps ENPP2, anticorps Enpp2, anticorps enpp2, anticorps enpp2.L, anticorps enpp2.S

Sujet: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Secreted

Poids moléculaire: 99 kDa

ID gène: 5168

UniProt: Q13822