Desmocollin 2 anticorps

N° du produit ABIN2856641

Détail du produit anti-Desmocollin 2 anticorps

Antigène: Desmocollin 2 (DSC2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmocollin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to Desmocollin 2 (desmocollin 2)
Desmocollin 2 antibody [C1C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Desmocollin 2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Desmocollin 2

Antigène: Desmocollin 2 (DSC2)

Autre désignation: desmocollin 2 (DSC2 Produits)

Synonymes: anticorps ARVD11, anticorps CDHF2, anticorps DG2, anticorps DGII/III, anticorps DSC3, anticorps AW228162, anticorps Dsc2a, anticorps Dsc2b, anticorps DSC2, anticorps desmocollin 2, anticorps DSC2, anticorps Dsc2

Sujet: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Cellular Localization: Cell membrane , Cell junction , desmosome

Poids moléculaire: 100 kDa

ID gène: 1824

UniProt: Q02487