DEDD anticorps

N° du produit ABIN2856831

Détail du produit anti-DEDD anticorps

Antigène: DEDD (Death Effector Domain Containing (DEDD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEDD est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to DEDD (death effector domain containing)
DEDD antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse leukocyte treated with CFA

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.42 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur DEDD

Antigène: DEDD (Death Effector Domain Containing (DEDD))

Autre désignation: death effector domain containing (DEDD Produits)

Synonymes: anticorps CASP8IP1, anticorps DEDD1, anticorps DEFT, anticorps FLDED1, anticorps Dedpro1, anticorps KE05, anticorps Deft, anticorps death effector domain containing, anticorps death effector domain-containing, anticorps DEDD, anticorps Dedd

Sujet: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cytoplasm , Nucleus , nucleolus

Poids moléculaire: 37 kDa

ID gène: 9191

UniProt: O75618