GPER anticorps (C-Term)

N° du produit ABIN2857010

L’anticorps Lapin Polyclonal anti-GPER a été validé pour WB et IHC. Il convient pour détecter GPER dans des échantillons de Humain.

Aperçu rapide pour GPER anticorps (C-Term) (ABIN2857010)

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPER est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: KO Validated

Détail du produit anti-GPER anticorps

Épitope: C-Term

Réactivité croisée: Humain, Porc

Attributs du produit: Rabbit Polyclonal antibody to GPR30 (G protein-coupled estrogen receptor 1)
GPR30 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPR30. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: GFP-human GPR30-transfected 293T cells (No boiling)

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GPER

Antigène: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Autre désignation: G protein-coupled estrogen receptor 1

Sujet: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Cellular Localization: Cell membrane, Multi-pass membrane protein , Endoplasmic reticulum membrane, Multi-pass membrane protein (By similarity) , Golgi apparatus membrane, Multi-pass membrane protein (By similarity)

Poids moléculaire: 42 kDa

ID gène: 2852

UniProt: Q99527

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process