SLC22A7 anticorps

N° du produit ABIN289967

Détail du produit anti-SLC22A7 anticorps

Antigène: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A7 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT2 by peptide affinity chromatography.

Immunogène: Partial peptide of Human Organic Anion Transporter 2 (OAT2)

Information d'application

Indications d'application: Working dilution for immunohistochemistry 5ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur SLC22A7

Antigène: SLC22A7 (Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7))

Autre désignation: Organic Anion Transporter 2 (OAT2) (SLC22A7 Produits)

Synonymes: anticorps NLT, anticorps OAT2, anticorps Oat2, anticorps oat2, anticorps nlt, anticorps slc22a7, anticorps im:6901703, anticorps im:7155670, anticorps oat2a, anticorps zgc:162334, anticorps oat2e, anticorps slc22a7b, anticorps zgc:63958, anticorps solute carrier family 22 member 7, anticorps solute carrier family 22 (organic anion transporter), member 7, anticorps solute carrier family 22 (organic anion transporter), member 7 L homeolog, anticorps solute carrier family 22 (organic anion transporter), member 7a, anticorps solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1, anticorps SLC22A7, anticorps Slc22a7, anticorps slc22a7.L, anticorps slc22a7a, anticorps slc22a7b.1

Sujet: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Organic anion transporter 2 (OAT2) is predicted 12 putative membrane-spanning protein, and which is expressed predominantly in the liver and only weakly in the kidney. OAT2 mediates the Na+-independent transport of organic anions, such as salicylate, and also mediates the transport of prostaglandin E2 (PGE2),methotrexate, acetylsalicylate and PAH (p-aminohippurate).This has been proved to be useful for immunohistochemistry .