FGF2 anticorps (AA 143-288)

N° du produit ABIN3020745

Cité dans 1 publication. Cet anticorps anti-FGF2 Polyclonal Lapin (ABIN3020745) détecte spécifiquement FGF2 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FGF2 anticorps (AA 143-288) (ABIN3020745)

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FGF2 anticorps

Épitope: AA 143-288

Séquence: PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 143-288 of human FGF2 (NP_001997.5).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-FGF2 (ABIN3020745)

Huang, Zhang, Zhang, Rehman, Tong, Qiu, Jiang, Iqbal, Shahzad, Shen, Li: "Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens." dans: Scientific reports, Vol. 8, Issue 1, pp. 3680, (2018) (PubMed).

Détails sur FGF2

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Autre désignation: FGF2

Sujet: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.,BFGF,FGF-2,FGFB,HBGF-2,Basic FGF,FGF2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Neuroscience,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,FGF2

Poids moléculaire: 17 kDa/21 kDa/22 kDa/30 kDa

ID gène: 2247

UniProt: P09038

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins