RAP1A anticorps (AA 50-150)

N° du produit ABIN3021200

Cet anticorps anti-RAP1A est un anticorps Lapin Polyclonal détectant RAP1A dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour RAP1A anticorps (AA 50-150) (ABIN3021200)

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RAP1A anticorps

Épitope: AA 50-150

Séquence: QCMLEILDTA GTEQFTAMRD LYMKNGQGFA LVYSITAQST FNDLQDLREQ ILRVKDTEDV PMILVGNKCD LEDERVVGKE QGQNLARQWC NCAFLESSAK S

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rap1A (NP_002875.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAP1A

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A

Sujet: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.,RAP1A,C21KG,G-22K,KREV-1,KREV1,RAP1,SMGP21,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RAP1A

Poids moléculaire: 20 kDa

ID gène: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor