MAPK10 anticorps (AA 175-464)

N° du produit ABIN3022948

L’anticorps Lapin Polyclonal anti-MAPK10 a été validé pour WB. Il convient pour détecter MAPK10 dans des échantillons de Humain.

Aperçu rapide pour MAPK10 anticorps (AA 175-464) (ABIN3022948)

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPK10 anticorps

Épitope: AA 175-464

Séquence: CGIKHLHSAG IIHRDLKPSN IVVKSDCTLK ILDFGLARTA GTSFMMTPYV VTRYYRAPEV ILGMGYKENV DIWSVGCIMG EMVRHKILFP GRDYIDQWNK VIEQLGTPCP EFMKKLQPTV RNYVENRPKY AGLTFPKLFP DSLFPADSEH NKLKASQARD LLSKMLVIDP AKRISVDDAL QHPYINVWYD PAEVEAPPPQ IYDKQLDERE HTIEEWKELI YKEVMNSEEK TKNGVVKGQP SPSGAAVNSS ESLPPSSSVN DISSMSTDQT LASDTDSSLE ASAGPLGCCR

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 175-464 of human JNK3 (NP_620448.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MAPK10

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: MAPK10

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,JNK3,JNK3A,PRKM10,SAPK1b,p493F12,p54bSAPK,MAPK10,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,MAPK10

Poids moléculaire: 48 kDa/52 kDa

ID gène: 5602

UniProt: P53779

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades