TYK2 anticorps (AA 750-850)

N° du produit ABIN3022988

Cet anticorps Lapin Polyclonal détecte spécifiquement TYK2 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour TYK2 anticorps (AA 750-850) (ABIN3022988)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TYK2 anticorps

Épitope: AA 750-850

Séquence: GTSPFIKLSD PGVGLGALSR EERVERIPWL APECLPGGAN SLSTAMDKWG FGATLLEICF DGEAPLQSRS PSEKEHFYQR QHRLPEPSCP QLATLTSQCL T

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human TYK2 (NP_003322.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2

Sujet: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,TYK2,IMD35,JTK1,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Immunology & Inflammation,TYK2

Poids moléculaire: 133 kDa

ID gène: 7297

UniProt: P29597

Pathways: Signalistation JAK/STAT, Hepatitis C