eIF4EBP1 anticorps (pSer65)

N° du produit ABIN3023532

L’anticorps anti-eIF4EBP1 Polyclonal Lapin est utilisé pour la détection de eIF4EBP1 dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour eIF4EBP1 anticorps (pSer65) (ABIN3023532)

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp eIF4EBP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-eIF4EBP1 anticorps

Épitope: pSer65

Séquence: RNSPV

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S65 of human Phospho-eIF4EBP1-S65 (NP_004086.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IP,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur eIF4EBP1

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Autre désignation: EIF4EBP1

Sujet: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.,4E-BP1,4EBP1,BP-1,PHAS-I,EIF4EBP1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Cardiovascular,Angiogenesis,Akt downstream targets,Protein phosphorylation,EIF4EBP1

Poids moléculaire: 12 kDa

ID gène: 1978

UniProt: Q13541

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling