CD11b anticorps

N° du produit ABIN3024274

Cet anticorps anti-CD11b Monoclonal Rat (Clone M1-70) (ABIN3024274) détecte spécifiquement CD11b dans FACS, IF et BR. L’anticorps est réactif avec des échantillons de Humain, Souris, Lapin, Babouin, Macaque rhésus, Chimpanzé et Cynomolgus.

Aperçu rapide pour CD11b anticorps (ABIN3024274)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain, Souris, Lapin, Babouin, Macaque rhésus, Chimpanzé, Cynomolgus

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

Clone: M1-70

Détail du produit anti-CD11b anticorps

Purification: Protein G affinity chromatography

Immunogène: B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,Functional Activity (Blocking): order BSA/azide free format

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD11b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b

Sujet: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

ID gène: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation