CD11b anticorps

N° du produit ABIN3024274

Cet anticorps anti-CD11b Monoclonal Rat (Clone M1-70) (ABIN3024274) détecte spécifiquement CD11b dans FACS, IF et Func. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD11b anticorps (ABIN3024274)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Classe de qualité: Carrier-free

Clone: M1-70

Détail du produit anti-CD11b anticorps

Fonction: CD11b Antibody / MAC-1 / ITGAM (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b

Sujet: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation