CLEC1A anticorps (N-Term)

N° du produit ABIN3024556

Détail du produit anti-CLEC1A anticorps

Antigène: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLEC1A est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A purified antibody

Immunogène: A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CLEC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CLEC1A

Antigène: CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))

Autre désignation: CLEC1 (CLEC1A Produits)

Synonymes: anticorps RGD1566110, anticorps CLEC1, anticorps 5930406N14Rik, anticorps C-type lectin domain family 1, member A, anticorps C-type lectin domain family 1 member A, anticorps C-type lectin domain family 1, member a, anticorps Clec1a, anticorps CLEC1A

Sujet: CLEC1 is a C-type lectin receptor and part of the 'Dectin-1 cluster' subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

ID gène: 51267