MALT1 anticorps (AA 701-808)

N° du produit ABIN3025289

Détail du produit anti-MALT1 anticorps

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Épitope: AA 701-808

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MALT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G purified

Immunogène: A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.

Clone: 4NMT-3

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titering of the MALT1 antibody may be required for optimal performance.

1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. IF: 1-2 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the MALT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur MALT1

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Autre désignation: MALT1 (MALT1 Produits)

Synonymes: anticorps malt1, anticorps MALT1, anticorps mlt, anticorps mlt1, anticorps MLT, anticorps MLT1, anticorps A630046N12, anticorps D430033E09Rik, anticorps MALT paracaspase 2, anticorps MALT1 paracaspase, anticorps MALT1 paracaspase S homeolog, anticorps paracaspase 3, anticorps malt2, anticorps MALT1, anticorps malt1.S, anticorps Malt1, anticorps PCASP3

Sujet: Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.

ID gène: 10892

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins