IFNA anticorps

N° du produit ABIN3026804

Cet anticorps Souris Monoclonal détecte spécifiquement IFNA dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour IFNA anticorps (ABIN3026804)

Antigène: IFNA (Interferon alpha (IFNA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA est non-conjugé

Application: ELISA

Clone: 2-52

Détail du produit anti-IFNA anticorps

Attributs du produit: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Purification: Protein G affinity chromatography

Immunogène: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the Interferon alpha antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur IFNA

Antigène: IFNA (Interferon alpha (IFNA))

Autre désignation: Interferon alpha

Sujet: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Pathways: Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome