RANKL anticorps

N° du produit ABIN302887

Cet anticorps Lapin Polyclonal détecte spécifiquement RANKL dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RANKL anticorps (ABIN302887)

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANKL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RANKL anticorps

Specificité: This antibody reacts to a 14 amino acid peptide from near the center of sRANK-L.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide

Information d'application

Indications d'application: Western Blot: 0,25 - 0,5 μg/mL. Immunohistochemistry: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur RANKL

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Autre désignation: CD254 / RANKL

Sujet: OPG ligand (OPGL,) a type II membrane protein, binds to a unique hematopoietic progenitor cell that is committed to the osteoclast lineage and stimulates the rapid induction of genes involved in osteoclast development. OPGL is expressed in the primitive mesenchymal cells, in hypertrophying chondrocytes and in areas undergoing primary ossification and modeling. This gene was independently isolated and called RANKL (receptor activator of NF-Kappa B ligand). RANKL was shown to augument the ability of dendritic cells to stimulate naive T-cell proliferation. A soluble form of the protein consisting of only the extracellular domain is called TRANCE.Synonyms: ODF, OPGL, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK Ligand, RANKL, Receptor activator of nuclear factor kappa B ligand, TNF-related activation-induced cytokine, TNFSF11, TRANCE, Tumor necrosis factor ligand superfamily member 11

ID gène: 8600

NCBI Accession: NP_003692

UniProt: O14788

Pathways: Signalisation NF-kappaB