COL4A1 anticorps (C-Term)

N° du produit ABIN3030546

Détail du produit anti-COL4A1 anticorps

Antigène: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4A1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Collagen IV COL4A1 (ELRTHVSRCQVCMRRT) was used as the immunogen for this Collagen IV antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Collagen IV antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Collagen IV antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur COL4A1

Antigène: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Autre désignation: Collagen IV (COL4A1) (COL4A1 Produits)

Synonymes: anticorps col4a1, anticorps wu:fc02g11, anticorps HANAC, anticorps ICH, anticorps POREN1, anticorps arresten, anticorps Bru, anticorps Col4a-1, anticorps Del(8)44H, anticorps Raw, anticorps Svc, anticorps collagen, type IV, alpha 5 (Alport syndrome), anticorps collagen type IV alpha 1 chain, anticorps collagen, type IV, alpha 1, anticorps col4a5, anticorps COL4A1, anticorps Col4a1

Sujet: Collagen alpha-1(IV) chain is a protein that in humans is encoded by the COL4A1 gene. Type IV collagen is the major structural component of glomerular basement membranes(GBM), forming a'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in COL4A1 exons 24 and 25 are associated with HANAC(autosomal dominant hereditary angiopathy with nephropathy,aneurysms, and muscle cramps).

UniProt: P02462

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding