Cullin 3 anticorps (Middle Region)

N° du produit ABIN3030578

Détail du produit anti-Cullin 3 anticorps

Antigène: Cullin 3 (CUL3)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 3 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human Cullin-3 (DVFERYYKQHLARRLLTNK) was used as the immunogen for this CUL3 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CUL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CUL3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Cullin 3

Antigène: Cullin 3 (CUL3)

Autre désignation: CUL3 (Cullin-3) (CUL3 Produits)

Synonymes: anticorps CUL-3, anticorps Cullin-3, anticorps CUL-3-A, anticorps Cullin-3-A, anticorps cul3, anticorps cul3a, anticorps CUL-3-B, anticorps Cullin-3-B, anticorps cul3b, anticorps wu:fc37e01, anticorps CUL3, anticorps ATCUL3, anticorps ATCUL3A, anticorps CUL3A, anticorps T24P13.25, anticorps cullin 3, anticorps cullin 3A, anticorps PHA2E, anticorps AI467304, anticorps AW146203, anticorps mKIAA0617, anticorps cullin 3, anticorps cullin 3 L homeolog, anticorps cullin 3 S homeolog, anticorps cullin-3, anticorps Cullin-3 (CUL-3), anticorps cullin 3a, anticorps CULlin, anticorps CUL3, anticorps cul3, anticorps cul3.L, anticorps cul3.S, anticorps PTRG_11586, anticorps Smp_117580, anticorps cul3a, anticorps Cul3, anticorps cul-3

Sujet: Cullin-3 is a protein that in humans is encoded by the CUL3 gene. Kipreos et al.(1996) identified a conserved gene family, designated cullins, with at least 5 members in nematodes, 6 in humans, and 3 in S. cerevisiae. Hartz (2012) mapped the gene to chromosome 2q36.2 based on an alignment of the CUL3 sequence with the genomic sequence (GRCh37). Sumara et al.(2007) found that KLHL9, KLHL13, and CUL-3 interacted directly in a 370-kD protein complex in HeLa cell lysates. Rondou et al.(2008) showed that interaction between KLHL12 and the CUL3 ubiquitin ligase complex directed ubiquitination of dopamine receptor D4(DRD4). KLHL12 interacted directly with CUL-3 and with the polymorphic intracellular loop-3 of D4. By immunoprecipitation analysis of HeLa cells and HCT116 human colon carcinoma cells expressing epitope-tagged proteins, Kigoshi et al.(2011) showed that KLHL7 interacted with CUL-3 and ROC1(RBX1).

UniProt: Q13618

Pathways: M Phase