CDK6 anticorps (C-Term)

N° du produit ABIN3030618

Cet anticorps anti-CDK6 est un anticorps Lapin Polyclonal détectant CDK6 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CDK6 anticorps (C-Term) (ABIN3030618)

Antigène: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK6 anticorps

Épitope: C-Term

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of mouse Cell division protein kinase 6 (AYGALNHPYFQDLERYKDNL) was used as the immunogen for this Cdk6 antibody (100% rat homology).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Cdk6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Cdk6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CDK6

Antigène: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Autre désignation: Cdk6

Sujet: Cell division protein kinase 6, also called Pistire, is an enzyme that in humans is encoded by the CDK6 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family. Radiation hybrid analysis and inclusion within a mapped clone place the gene at 7q21. Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation and promotes G1/S transition. This gene also involved in initiation and maintenance of cell cycle exit during cell differentiation. It prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types. CDK6 also plays a role in promoting the proliferation of beta-cells in pancreatic islets of Langerhans.

UniProt: Q64261

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases