FOXM1 anticorps (AA 411-763)

N° du produit ABIN3030988

Détail du produit anti-FOXM1 anticorps

Antigène: FOXM1 (Forkhead Box M1 (FOXM1))

Épitope: AA 411-763

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXM1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the FOXM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the FOXM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur FOXM1

Antigène: FOXM1 (Forkhead Box M1 (FOXM1))

Autre désignation: FOXM1 (FOXM1 Produits)

Synonymes: anticorps FKHL16, anticorps FOXM1B, anticorps HFH-11, anticorps HFH11, anticorps HNF-3, anticorps INS-1, anticorps MPHOSPH2, anticorps MPP-2, anticorps MPP2, anticorps PIG29, anticorps TGT3, anticorps TRIDENT, anticorps FOXM1, anticorps AA408308, anticorps AW554517, anticorps BB238854, anticorps Fkh16, anticorps Foxm1b, anticorps HFH-11B, anticorps Mpm2, anticorps WIN, anticorps Trident, anticorps fkhl16, anticorps foxm1l, anticorps hfh-11, anticorps mpp2, anticorps zgc:63854, anticorps forkhead box M1, anticorps forkhead box M1 S homeolog, anticorps FOXM1, anticorps Foxm1, anticorps foxm1, anticorps foxm1.S

Sujet: Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.

ID gène: 2305

Pathways: Positive Regulation of Response to DNA Damage Stimulus