HYAL3 anticorps (C-Term)

N° du produit ABIN3031265

Détail du produit anti-HYAL3 anticorps

Antigène: HYAL3 (Hyaluronidase-3 (HYAL3))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYAL3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Hyaluronoglucosaminidase 3 (SHQRCHGHGRCARRD) was used as the immunogen for this HYAL3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the HYAL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HYAL3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HYAL3

Antigène: HYAL3 (Hyaluronidase-3 (HYAL3))

Autre désignation: HYAL3 (HYAL3 Produits)

Synonymes: anticorps HYAL1, anticorps HYAL3, anticorps Hyal-3, anticorps HYAL-3, anticorps LUCA-3, anticorps LUCA3, anticorps Hyl3, anticorps hyaluronoglucosaminidase 3, anticorps HYAL3, anticorps Hyal3

Sujet: Hyaluronoglucosaminidase 3 is anenzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, and Minna14. By Northern blot analysis, expression of a 2.1-kb transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process