MFN1 anticorps (N-Term)

N° du produit ABIN3031817

Détail du produit anti-MFN1 anticorps

Antigène: MFN1 (Mitofusin 1 (MFN1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminal of human Mitofusin 1 (DQLLEFVTEGSHFVEATYKNPELDRIA) was used as the immunogen for this MFN1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the MFN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MFN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MFN1

Antigène: MFN1 (Mitofusin 1 (MFN1))

Autre désignation: MFN1 (MFN1 Produits)

Synonymes: anticorps mfn1, anticorps zgc:66150, anticorps mitofusin-1, anticorps MFN1, anticorps MFN2, anticorps hfzo1, anticorps hfzo2, anticorps 2310002F04Rik, anticorps 6330416C07Rik, anticorps D3Ertd265e, anticorps HR2, anticorps mKIAA4032, anticorps Fzo1b, anticorps mitofusin 1b, anticorps mitofusin 1, anticorps mitofusin 1 S homeolog, anticorps mfn1b, anticorps MFN1, anticorps mfn1.S, anticorps mfn1, anticorps Mfn1

Sujet: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is a mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. It has two key domains, One is a coiled-coil region that mediates MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression causes perinuclear mitochondrial clustering.

ID gène: 55669