OSBP anticorps (Middle Region)
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- Antigène Voir toutes OSBP Anticorps
- OSBP (Oxysterol Binding Protein (OSBP))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OSBP est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the middle region of human Oxysterol-Binding Protein (WQKSLQYERDQRIRL) was used as the immunogen for this OSBP antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product OSBP Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the OSBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the OSBP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- OSBP (Oxysterol Binding Protein (OSBP))
- Autre désignation
- OSBP (OSBP Produits)
- Synonymes
- anticorps CG6708, anticorps Dmel\\CG6708, anticorps OSBP-Dm, anticorps osbp, anticorps OSBP1, anticorps 1110018F06Rik, anticorps AW559088, anticorps mKIAA4220, anticorps Oxysterol binding protein, anticorps oxysterol binding protein, anticorps Osbp, anticorps OSBP
- Sujet
- Oxysterol-Binding Protein is a protein that in humans is encoded by the OSBP gene. Im et al.(2005) reported the structure of the full-length yeast oxysterol-binding-protein Osh4, a member of the OSBP-related protein (ORP) family, at 1.5- to 1.9-angstrom resolution in complexes with ergosterol, cholesterol, and 7-, 20- and 25-hydroxy cholesterol. Moreira et al.(2001) refined the localization of the OSBP1 gene to chromosome 11q12.1 by radiation hybrid analysis. Wang et al.(2005) found that OSBP functions as a cholesterol-binding scaffolding protein coordinating the activity of 2 phosphatases to control the extracellular signal-regulated kinase (ERK) signaling pathway. Cytosolic OSBP formed an approximately 440-kD oligomer with a member of the PTPPBS family of tyrosine phosphatases, the serine/threonine phosphatase PP2A, and cholesterol.
- UniProt
- P22059
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