P2RX2 anticorps (AA 139-471)

N° du produit ABIN3032407

Détail du produit anti-P2RX2 anticorps

Antigène: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Épitope: AA 139-471

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 139-471) was used as the immunogen for this P2X2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the P2X2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the P2X2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur P2RX2

Antigène: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Autre désignation: P2X2 (P2RX2 Produits)

Synonymes: anticorps DFNA41, anticorps P2X2, anticorps P2X2a, anticorps P2x2, anticorps p2xr2, anticorps P2RX2, anticorps purinergic receptor P2X 2, anticorps purinergic receptor P2X, ligand-gated ion channel, 2, anticorps P2RX2, anticorps P2rx2, anticorps p2rx2

Sujet: The P2RX2 gene encodes the P2X2 receptor, which assembles as a trimer to form a ligand-gated ion channel gated by extracellular ATP. P2X2 receptors mediate a variety of cellular responses, including excitatory postsynaptic responses in sensory neurons. The product of this gene belongs to the family of purinoceptors for ATP. P2RX2 is mapped to 12q24.33. It has been found that ATP-activated P2RX2 influenced OHC electromotility, a stimulus-induced change in hair cell length that functions as an amplifier to determine hearing sensitivity and frequency selectivity. Additionally, P2RX2 channels were necessary for development of the temporary threshold shift.

ID gène: 22953

Pathways: Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity