SERPINA3
Reactivité: Humain
WB, IF
Hôte: Souris
Polyclonal
unconjugated
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the SERPINA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the SERPINA3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
SERPINA3
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
anticorps SERPINA3-1, anticorps Pi2, anticorps AACT, anticorps ACT, anticorps GIG25, anticorps A1AT, anticorps PI, anticorps alpha-1-PI, anticorps AAT, anticorps Pi, anticorps Spi1, anticorps SERPINA3-5, anticorps serpina3, anticorps serpin A3-5, anticorps serpin family A member 3, anticorps alpha-1-antiproteinase F precursor, anticorps serpin family A member 1, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog, anticorps LOC396684, anticorps SERPINA3, anticorps LOC100008973, anticorps SERPINA1, anticorps Serpina1, anticorps SPIA5, anticorps serpina3.L
Sujet
Alpha 1-antichymotrypsin, also called serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 or GIG24, is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. This gene is mapped to 14q32.13. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimers disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.