SERPINH1 anticorps (AA 247-418)

N° du produit ABIN3032548

Détail du produit anti-SERPINH1 anticorps

Antigène: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Épitope: AA 247-418

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 247-418) was used as the immunogen for this HSP47 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the HSP47 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HSP47 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur SERPINH1

Antigène: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Autre désignation: HSP47 (SERPINH1 Produits)

Synonymes: anticorps AsTP3, anticorps CBP1, anticorps CBP2, anticorps HSP47, anticorps OI10, anticorps PPROM, anticorps RA-A47, anticorps SERPINH2, anticorps gp46, anticorps SERPINH1, anticorps DKFZp468B197, anticorps cb216, anticorps hsp, anticorps hsp47, anticorps id:ibd5060, anticorps wu:fc56b02, anticorps BERF-1, anticorps Cbp1, anticorps Cbp2, anticorps Hsp47, anticorps J6, anticorps Serpinh2, anticorps colligin, anticorps astp3, anticorps cbp1, anticorps cbp2, anticorps pig14, anticorps pprom, anticorps ra-a47, anticorps serpinh2, anticorps serpin family H member 1, anticorps serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b, anticorps serpin H1, anticorps selenoprotein K, anticorps serine (or cysteine) peptidase inhibitor, clade H, member 1, anticorps serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog, anticorps SERPINH1, anticorps serpinh1b, anticorps LOC100009353, anticorps Selenok, anticorps Serpinh1, anticorps serpinh1.L

Classe de substances: Viral Protein

Sujet: Heat shock protein 47, also known as SERPINH1, is a serpin which serves as a human chaperone protein for collagen. It is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. HSP47 localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.

ID gène: 871