NLRP1
Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Rat, Cobaye, Porc, Lapin
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunocytochemistry. Western Blot (1-2 μg/mL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Death Effector Filament-forming Ced 4 like Apoptosis Protein (DEFCAP) is a novel apoptotic protein of the mammalian Ced 4 family. It has two isoforms: DEFCAP-Land DEFCAP-S. The deduced amino acid sequences of these two alternately spliced isoforms only differ by 44amino acids at the C-terminus. DEFCAP contains a caspase recruitment domain (CARD), a domain that with the proper stimulation can recruit caspases to form cytoplasmic structures called death effector filaments, which in turn initiate the apoptotic signaling pathway.Synonyms: Caspase recruitment domain-containing protein 7, DEFCAP, Death effector filament-forming ced-4-like apoptosis protein, KIAA0926, LRR and PYD domains-containing protein 1, NAC, NACHT, NALP1, Nucleotide-binding domain and caspase recruitment domain