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NLRP1 anticorps

NLRP1 Reactivité: Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074850
  • Antigène Voir toutes NLRP1 Anticorps
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Reactivité
    • 38
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 35
    • 2
    • 1
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NLRP1 est non-conjugé
    Application
    • 29
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse NLRP1
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  • Indications d'application
    IHC/IF (M,R) 1:500-1:2000/1:250-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Autre désignation
    NLRP1 (NLRP1 Produits)
    Synonymes
    anticorps CARD7, anticorps CIDED, anticorps CLR17.1, anticorps DEFCAP, anticorps DEFCAP-L/S, anticorps NAC, anticorps NALP1, anticorps PP1044, anticorps SLEV1, anticorps VAMAS1, anticorps NLR family pyrin domain containing 1, anticorps NLRP1, anticorps Nlrp1
    Sujet
    NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
    ID gène
    195046
    NCBI Accession
    NP_001004142
    UniProt
    Q2LKU9
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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