TICAM2 anticorps (C-Term)

N° du produit ABIN303369

Cet anticorps anti-TICAM2 Polyclonal Lapin (ABIN303369) détecte spécifiquement TICAM2 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TICAM2 anticorps (C-Term) (ABIN303369)

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TICAM2 anticorps

Épitope: C-Term

Specificité: This antibody recognises Toll-like Receptor Adaptor Molecule 2 (TICAM2).

Purification: Purified

Immunogène: Peptide corresponding to amino acids at the C terminus of human TIRP.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (10 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid cycles of freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Détails sur TICAM2

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: TICAM2 / TRAM

Sujet: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kB. Expression of TIRP appears to be essential for TLR4 signalling.Synonyms: Putative NF-kappa-B-activating protein 502, TICAM-2, TIR domain-containing adapter molecule 2, TIRAP3, TIRP, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein

ID gène: 100302736

NCBI Accession: NP_001157941

UniProt: Q86XR7

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades