PTGS1 anticorps (AA 318-599)

N° du produit ABIN3042528

Détail du produit anti-PTGS1 anticorps

Antigène: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Épitope: AA 318-599

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC-P in Human,Rat.

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: prostaglandin-endoperoxide synthase 1
Protein Name: Prostaglandin G/H synthase 1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human COX1 recombinant protein (Position: E318-L599). Human COX1 shares 90% and 89% amino acid (aa) sequence identity with mouse and ratCOX1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-PTGS1 (ABIN3042528)

Ahmadieh, Nourinia, Hafezi-Moghadam, Sabbaghi, Nakao, Zandi, Yaseri, Tofighi, Akbarian: "Intravitreal injection of a Rho-kinase inhibitor (fasudil) combined with bevacizumab versus bevacizumab monotherapy for diabetic macular oedema: a pilot randomised clinical trial." dans: The British journal of ophthalmology, (2018) (PubMed).

Zhen, Zong, Gao, Cao, Jiang, Chen, Wang, Sun, Peng, Bai, Li: "Preparation and characterization of a novel aspirin derivative with anti-thrombotic and gastric mucosal protection properties." dans: PLoS ONE, Vol. 9, Issue 6, pp. e98513, (2015) (PubMed).

Duan, Que, Lv, Li, Yin, Zhang: "Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor." dans: Neural regeneration research, Vol. 7, Issue 34, pp. 2705-12, (2014) (PubMed).

Détails sur PTGS1

Antigène: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Autre désignation: PTGS1 (PTGS1 Produits)

Synonymes: anticorps COX-1, anticorps cox-1, anticorps PTGS1, anticorps Ptgs1, anticorps COX1, anticorps Cox-1, anticorps Cox-3, anticorps PGHS-1, anticorps PHS 1, anticorps Pghs1, anticorps Cox1, anticorps Cox3, anticorps cox1, anticorps zCOX-1, anticorps COX3, anticorps PCOX1, anticorps PES-1, anticorps PGG/HS, anticorps PGHS1, anticorps PHS1, anticorps PTGHS, anticorps COX-3, anticorps prostaglandin-endoperoxide synthase 1, anticorps cyclooxygenase-1, anticorps prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase), anticorps prostaglandin-endoperoxide synthase 1 S homeolog, anticorps PTGS1, anticorps cox-1, anticorps Ptgs1, anticorps ptgs1, anticorps ptgs1.S

Sujet: Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene was approximately 40 kb long, with 11 protein-coding exons. There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the PTGS1 gene maps to chromosome 9. Human prostaglandin endoperoxide synthase exhibited 91 % amino acid identity with the sheep enzyme. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

Synonyms: COX 1 antibody|COX 3 antibody|COX-1 antibody|COX1 antibody|COX3 antibody|Cyclooxygenase 1 antibody|Cyclooxygenase 3, included antibody|Cyclooxygenase-1 antibody|Cyclooxygenase1 antibody|EC 1.14.99.1 antibody|Partial COX1 proteins, included antibody|PCOX 1 antibody|PCOX1 antibody|PGG/HS antibody|PGH synthase 1 antibody|PGH1_HUMAN antibody|PGHS 1 antibody|PGHS-1 antibody|PGHS1 antibody|PHS 1 antibody|PHS1 antibody|Prostaglandin endoperoxide synthase 1 antibody|Prostaglandin G/H synthase 1 antibody|Prostaglandin G/H synthase and cyclooxygenase antibody|Prostaglandin H Synthase 1 antibody|Prostaglandin H2 synthase 1 antibody|Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody|Prostaglandin-endoperoxide synthase 1 antibody|PTGHS antibody|PTGS 1 antibody|PTGS1 antibody

UniProt: P23219