FGF2 anticorps (AA 143-288)

N° du produit ABIN3042812

Détail du produit anti-FGF2 anticorps

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Épitope: AA 143-288

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Fibroblast growth factor 2(FGF2) detection. Tested with WB, IHC-P, ELISA in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Fibroblast growth factor 2(FGF2) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: fibroblast growth factor 2(basic)
Protein Name: Fibroblast growth factor 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FGF2 recombinant protein(Position: P143-S288).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Human

Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-FGF2 (ABIN3042812)

Xiong, Sun, Liu, Xu, He et al.: "Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apoptosis and expression of vascular endothelial growth factor and basic fibroblast growth factor in human umbilical vein ..." dans: Oncology letters, Vol. 11, Issue 1, pp. 491-499, (2016) (PubMed).

Wang, Wang, Yao, Wu, Tang, Gu, Li: "The fibroblast growth factor-2 arrests Mycobacterium avium sp. paratuberculosis growth and immunomodulates host response in macrophages." dans: Tuberculosis (Edinburgh, Scotland), Vol. 95, Issue 4, pp. 505-14, (2015) (PubMed).

Hu, Zhang, Ren, Deng, Cai, Lei, Ping: "Effect of vacuum-assisted closure combined with open bone grafting to promote rabbit bone graft vascularization." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1200-6, (2015) (PubMed).

Yu, Zhang, Jiang, Wang, Zhang: "Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction." dans: Molecular medicine reports, Vol. 12, Issue 5, pp. 6718-26, (2015) (PubMed).

Ai, Liu, Sun: "Advanced glycation end-products stimulate basic fibroblast growth factor expression in cultured Müller cells." dans: Molecular medicine reports, Vol. 7, Issue 1, pp. 16-20, (2014) (PubMed).

Zhou, Ma, Si, Li, Xu, Tu, Wang: "MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth." dans: Cancer letters, Vol. 333, Issue 2, pp. 159-69, (2013) (PubMed).

Détails sur FGF2

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Autre désignation: FGF2 (FGF2 Produits)

Synonymes: anticorps BFGF, anticorps FGF-2, anticorps FGFB, anticorps HBGF-2, anticorps Fgf-2, anticorps Fgfb, anticorps bFGF, anticorps fibroblast growth factor 2, anticorps fibroblast growth factor 2 (basic), anticorps FGF2, anticorps Fgf2, anticorps fgf2

Sujet: FGF2 has been implicated in a multitude of physiologic and pathologic processes, including limb development, angiogenesis, wound healing, and tumor growth. Human FGF2 shares 96 % and 97 % amino acid sequence homology with mouse and rat respectively. FGF2 belongs to the fibroblast growth factor(FGF) family. Fibroblast growth factors(FGFs) exhibit widespread mitogenic and neurotrophic activities. Nine members of the family are currently known, and FGF-1 and FGF-2 are present in relatively high levels in CNS. FGF-2 is expressed by at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary.

Synonyms: Basic fibroblast growth factor antibody|Basic fibroblast growth factor bFGF antibody|BFGF antibody| Fgf2 antibody|FGFB antibody|Fibroblast Growth Factor 2 basic antibody|HBGF 2 antibody|HBGF-2 antibody|Heparin binding growth factor 2 antibody|Heparin-binding growth factor 2 antibody|Prostatropin antibody

UniProt: P09038

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins