FMO4 anticorps (N-Term)

N° du produit ABIN3043006

Cet anticorps Lapin Polyclonal détecte spécifiquement FMO4 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FMO4 anticorps (N-Term) (ABIN3043006)

Antigène: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FMO4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FMO4 anticorps

Épitope: AA 75-92, N-Term

Fonction: Anti-Flavin containing monooxygenase 4/FMO4 Antibody Picoband®

Séquence: HEDYPNFMNH EKFWDYLQ

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Flavin containing monooxygenase 4/FMO4 Antibody (ABIN3043006). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Flavin containing monooxygenase 4, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Dolphin, C. T., Shephard, E. A., Povey, S., Smith, R. L., Phillips, I. R. Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family. Biochem. J. 287: 261-267, 1992. 2. Lawton, M. P., Cashman, J. R., Cresteil, T., Dolphin, C. T., Elfarra, A. A., Hines, R. N., Hodgson, E., Kimura, T., Ozols, J., Phillips, I. R., Philpot, R. M., Poulsen, L. L., Rettie, A. E., Shephard, E. A., Williams, D. E., Ziegler, D. M. A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch. Biochem. Biophys. 308: 254-257, 1994. 3. Phillips, I. R., Dolphin, C. T., Clair, P., Hadley, M. R., Hutt, A. J., McCombie, R. R., Smith, R. L., Shephard, E. A.The molecular biology of the flavin-containing monooxygenases of man. Chem. Biol. Interact. 96: 17-32, 1995.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FMO4

Antigène: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Autre désignation: FMO4

Sujet:

Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 4,1.14.13.8,Dimethylaniline oxidase 4,Hepatic flavin-containing monooxygenase 4,FMO 4,FMO4,FMO2,

Tissue Specificity: Liver.

Background: FMO4 (Flavin-containing monooxygenase 4) also known as FMO2, FORMERLY or FMO, ADULT LIVER FORM, is an enzyme that in humans is encoded by the FMO4 gene. By PCR analysis, Dolphin et al. (1992) mapped the FMO4 gene to chromosome 1. Southern blot hybridization with single exon probes demonstrated that human FMO4 and FMO1 are, in each case, the product of a single gene. Lawton et al. (1994) proposed a reclassification of mammalian FMOs. Under this system, FMO2 described by Dolphin et al. (1992) is now designated FMO4.

Sequence Similarities: Belongs to the FMO family.

Poids moléculaire: 95 kDa

UniProt: P31512