SDHA anticorps (N-Term)

N° du produit ABIN3043074

Détail du produit anti-SDHA anticorps

Antigène: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Épitope: AA 113-128, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDHA est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.

Séquence: NMEEDNWRWH FYDTVK

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein(Fp)
Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SDHA(113-128aa NMEEDNWRWHFYDTVK), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SDHA

Antigène: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Autre désignation: SDHA (SDHA Produits)

Synonymes: anticorps CG17246, anticorps Dmel\\CG17246, anticorps Scs-fp, anticorps Sdh, anticorps Sdha, anticorps scs-fp, anticorps sdh, anticorps CMD1GG, anticorps FP, anticorps PGL5, anticorps SDH1, anticorps SDH2, anticorps SDHF, anticorps 1500032O14Rik, anticorps 2310034D06Rik, anticorps 4921513A11, anticorps C81073, anticorps im:7141001, anticorps zgc:56051, anticorps Fp, anticorps sdha-b, anticorps Succinate dehydrogenase, subunit A (flavoprotein), anticorps succinate dehydrogenase complex flavoprotein subunit A, anticorps succinate dehydrogenase complex, subunit A, flavoprotein (Fp), anticorps succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog, anticorps SdhA, anticorps SDHA, anticorps Sdha, anticorps sdha, anticorps sdha.S

Sujet: SDHA(Succinate dehydrogenase complex, subunit a, flavoprotein), also called SDH1, HOMOLOG OF, is a protein that in humans is encoded by the SDHA gene. The SDHA gene is mapped on 5p15.33. The SDHA gene is highly polymorphic. The gene that codes for the SDHA protein is nuclear, even though the protein is located in the inner membrane of the mitochondria. Heterozygous carriers of an SDHA mutation do not developparagangliomas as has been seen for mutations in the other subunits. In vitro functional expression studies in the yeast homolog showed that the mutation resulted in a loss of SDH activity and rendered the mutant SDHA protein more susceptible to proteolysis. The findings indicated that SDHA, like other SDH subunits, can act as a tumor suppressor gene.

Synonyms: CMD1GG antibody|DHSA_HUMAN antibody|Flavoprotein subunit of complex II antibody|Fp antibody|PGL5 antibody|SDH 2 antibody|SDH1 antibody|SDH2 antibody|SDHA antibody|SDHF antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit mitochondrial antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial antibody|Succinate dehydrogenase complex flavoprotein subunit antibody|Succinate dehydrogenase complex flavoprotein subunit precursor antibody|Succinate dehydrogenase complex subunit A antibody|Succinate Dehydrogenase Complex subunit A Flavoprotein antibody

UniProt: P31040