TRAM2 anticorps (C-Term)

N° du produit ABIN3044050

Détail du produit anti-TRAM2 anticorps

Antigène: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Épitope: AA 309-325, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAM2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.

Séquence: RFIHSQLRHW REYWKEQ

Réactivité croisée (Details): Predicted Cross Reactivity: human, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: translocation associated membrane protein 2
Protein Name: Translocating chain-associated membrane protein 2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse TRAM2(309-325aa RFIHSQLRHWREYWKEQ), identical to the related rat sequence, and different from the related human sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Predicted Species: Human, Rat, The detection limit for TRAM2 is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TRAM2

Antigène: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Autre désignation: TRAM2 (TRAM2 Produits)

Synonymes: anticorps C330003D03Rik, anticorps wu:fb20c11, anticorps wu:fi23a12, anticorps zgc:111902, anticorps zgc:55869, anticorps zgc:76937, anticorps tram2, anticorps translocation associated membrane protein 2, anticorps tram-like protein, anticorps TraM-like protein, anticorps translocating chain-associating membrane protein 2, anticorps translocation associated membrane protein 2 L homeolog, anticorps TRAM2, anticorps CJE0444, anticorps BT_p548215, anticorps traM, anticorps CJJ81176_0418, anticorps Tram2, anticorps tram2, anticorps tram2.L

Sujet: TRAM2(Translocation-Associating Membrane Protein 2), also called KIAA0057, is a protein that in humans is encoded by the TRAM2 gene. TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum(ER) membrane. By genomic sequence analysis, Onuchic et al.(1999) mapped the TRAM2 gene to chromosome 6p21.1-p12 near the PKHD1 gene. Upon activation, quiescent hepatic stellate cells proliferate, change morphologically into myofibroblasts, and increase their synthesis of extracellular matrix proteins. Stefanovic et al.(2004) demonstrated that both TRAM2 and collagen type I are upregulated in activated rat and human hepatic stellate cells.

Synonyms: C330003D03Rik antibody|KIAA0057 antibody|MGC25725 antibody|OTTHUMP00000016607 antibody|TRAM like protein antibody|Tram2 antibody|TRAM2_HUMAN antibody|Translocating chain associating membrane protein 2 antibody|Translocating chain-associated membrane protein 2 antibody|Translocation associated membrane protein 2 antibody

UniProt: Q924Z5