CAMKK1 anticorps (N-Term)

N° du produit ABIN3044431

Détail du produit anti-CAMKK1 anticorps

Antigène: CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))

Épitope: AA 10-31, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMKK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: QDPRAELVDR VAAINVAHLE EA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: calcium/calmodulin-dependent protein kinase kinase 1, alpha
Protein Name: Calcium/calmodulin-dependent protein kinase kinase 1(CaM-KK 1/CaM-kinase kinase 1/CaMKK 1)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK(10-31aa QDPRAELVDRVAAINVAHLEEA), different from the related human sequence by three amino acids, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CAMKK1

Antigène: CAMKK1 (Calcium/calmodulin-Dependent Protein Kinase Kinase 1, alpha (CAMKK1))

Autre désignation: CAMKK1 (CAMKK1 Produits)

Synonymes: anticorps cam-kk, anticorps cam-kk1, anticorps camkka, anticorps zgc:113440, anticorps CAMKK1, anticorps CaM-KK, anticorps CAMKKA, anticorps AI846603, anticorps CaMKKalpha, anticorps Camkk, anticorps calcium/calmodulin-dependent protein kinase kinase 1 S homeolog, anticorps calcium/calmodulin dependent protein kinase kinase 1, anticorps calcium/calmodulin-dependent protein kinase kinase 1, alpha a, anticorps calcium/calmodulin-dependent protein kinase kinase 1, anticorps calcium/calmodulin-dependent protein kinase kinase 1, alpha, anticorps camkk1.S, anticorps CAMKK1, anticorps camkk1a, anticorps camkk1, anticorps Camkk1

Sujet: CAMKK1, Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The CAMKK1 gene is mapped to chromosome 17. The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.Camkk1binds calmodulin and activated Camk4 with a 6-fold increase in total activity and a 100-fold increase in Camk4 Ca(2+)-independent activity. Camkk1 catalyzed a 10-fold increase in the total activity of Camk1 and had no effect on Camk2. Cotransfection of COS-7 cells with Camkk1 and Camk4 resulted in a 14-fold increase in CRE-binding protein-dependent transcription compared with Camk4 alone, suggesting that Camkk1 enhances Camk4-mediated transcriptional regulation.

Synonyms: Ca2+/calmodulin-dependent protein kinase kinase alpha antibody|Calcium/calmodulin dependent protein kinase kinase antibody|Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody|Calcium/calmodulin dependent protein kinase kinase 1 antibody|Calcium/calmodulin dependent protein kinase kinase alpha antibody|Calcium/calmodulin-dependent protein kinase kinase 1 antibody|Calcium/calmodulin-dependent protein kinase kinase alpha antibody|CaM kinase kinase alpha antibody|CaM-kinase IV kinase antibody|CaM-kinase kinase 1 antibody|CaM-kinase kinase alpha antibody|CaM-KK 1 antibody|CaM-KK alpha antibody|CaMKK 1 antibody|CaMKK alpha antibody|CAMKK alpha protein antibody|CaMKK antibody|CAMKK1 antibody|CAMKKA antibody|DKFZp761M0423 antibody|KKCC1_HUMAN antibody|MGC34095 antibody|OTTMUSP00000006419 antibody

Pathways: AMPK Signaling