TNFSF8 anticorps (AA 63-234)

N° du produit ABIN3044499

Détail du produit anti-TNFSF8 anticorps

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Épitope: AA 63-234

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF8 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 8(TNFSF8) detection. Tested with IHC-P, FCM in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 8(TNFSF8) detection. Tested with IHC-P, FCM in Human.
Gene Name: tumor necrosis factor superfamily member 8
Protein Name: Tumor necrosis factor ligand superfamily member 8

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD153 recombinant protein (Position: Q63-D234). Human CD153 shares 75% amino acid (aa) sequence identity with mouse CD153.

Isotype: IgG

Information d'application

Indications d'application: IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur TNFSF8

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Autre désignation: TNFSF8 (TNFSF8 Produits)

Synonymes: anticorps CD153, anticorps CD30LG, anticorps Cd30l, anticorps CD30L, anticorps TNFRSF8, anticorps TNFSF8, anticorps tumor necrosis factor (ligand) superfamily, member 8, anticorps TNF superfamily member 8, anticorps tumor necrosis factor superfamily member 8, anticorps Tnfsf8, anticorps TNFSF8

Sujet: CD153 is a ligand for CD30. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: CD153 antibody|CD153 antigen antibody|CD30 antigen ligand antibody|CD30 L antibody|CD30 ligand antibody|CD30-L antibody|CD30L antibody|CD30LG antibody|MGC138144 antibody|TNFL8_HUMAN antibody|Tnfsf8 antibody|Tumor necrosis factor (ligand) superfamily member 8 antibody|Tumor necrosis factor ligand superfamily member 8 antibody

ID gène: 944

UniProt: P32971