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CDC25C anticorps (C-Term)

Il existe 1 publication pour ce produit. L’anticorps anti-CDC25C Polyclonal Lapin est utilisé pour la détection de CDC25C dans des échantillons de Humain. Il a été validé pour WB.
N° du produit ABIN3044504
500,50 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 8 à 12 jours ouvrables

Aperçu rapide pour CDC25C anticorps (C-Term) (ABIN3044504)

Antigène

Voir toutes CDC25C Anticorps
CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivité

  • 126
  • 48
  • 40
  • 16
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 112
  • 16
Lapin

Clonalité

  • 97
  • 31
Polyclonal

Conjugué

  • 67
  • 6
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp CDC25C est non-conjugé

Application

  • 104
  • 51
  • 46
  • 30
  • 26
  • 26
  • 20
  • 17
  • 13
  • 10
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 26
    • 19
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 435-473, C-Term

    Fonction

    Anti-Cdc25C Antibody

    Séquence

    MHHQDHKTEL LRCRSQSKVQ EGERQLREQI ALLVKDMSP

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Cdc25C Antibody (ABIN3044504). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc25C, different from the related mouse sequence by ten amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." dans: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

  • Antigène

    CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

    Autre désignation

    CDC25C

    Sujet

    Synonyms: M-phase inducer phosphatase 3,3.1.3.48,Dual specificity phosphatase Cdc25C,CDC25C,

    Tissue Specificity: Present only in testis (at protein level). .

    Background: M-phase inducer phosphatase 3?is an?enzyme?that in humans is encoded by the?CDC25C?gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It s dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

    Poids moléculaire

    53 kDa

    ID gène

    995

    UniProt

    P30307

    Pathways

    Cycle Cellulaire, M Phase
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