CDC25C anticorps (C-Term)

N° du produit ABIN3044504

Il existe 1 publication pour ce produit. L’anticorps anti-CDC25C Polyclonal Lapin est utilisé pour la détection de CDC25C dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CDC25C anticorps (C-Term) (ABIN3044504)

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC25C anticorps

Épitope: C-Term

Fonction: Anti-Cdc25C Antibody

Séquence: MHHQDHKTEL LRCRSQSKVQ EGERQLREQI ALLVKDMSP

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by ten amino acids.

Attributs du produit: Anti-Cdc25C Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc25C, different from the related mouse sequence by ten amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CDC25C (ABIN3044504)

Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." dans: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

Détails sur CDC25C

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Autre désignation: CDC25C

Sujet:

Background: M-phase inducer phosphatase 3?is an?enzyme?that in humans is encoded by the?CDC25C?gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It s dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Gene Full Name: cell division cycle 25C

Poids moléculaire: 53 kDa

ID gène: 995

UniProt: P30307

Pathways: Cycle Cellulaire, M Phase