Bcl-2 anticorps
Aperçu rapide pour Bcl-2 anticorps (ABIN306555)
Antigène
Voir toutes Bcl-2 (BCL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Attributs du produit
- mbcl2, bcl2, mouse anti mouse bcl2,The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16 kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. It can be used in immunohistochemistry as an indicator of HPV infection in cervical and head and neck (pre)malignancies.
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Purification
- Protein A/G Chromatography
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Immunogène
- A recombinant full length p16 protein recognizing a 16kDa protein
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Isotype
- IgG1
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Indications d'application
- Applications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)
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Restrictions
- For Research Use only
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Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Autre désignation
- bcl-2
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Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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