ErbB2/Her2 anticorps (full length)
Aperçu rapide pour ErbB2/Her2 anticorps (full length) (ABIN306627)
Antigène
Voir toutes ErbB2/Her2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- full length
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Fonction
- Sheep anti Human HER2/neu
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Attributs du produit
- c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25 % of primary breast and ovarian tumors were found to overexpress the protein.
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Purification
- Ammonium Sulfate Precipitation
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Immunogène
- Full-length recombinant c-erbB-2/HER2/neu protein.
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Isotype
- IgG
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Indications d'application
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Autre désignation
- c-ErbB-2
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Sujet
- P185erbB2, MLN 19, CD340, c-ErbB-2
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UniProt
- P04626
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Antigène
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