AKAP12 anticorps

N° du produit ABIN306674

L’anticorps anti-AKAP12 Polyclonal produit chez le Mouton a été validé pour WB. Il convient pour la détection de AKAP12 dans des échantillons provenant de Rat. }

Aperçu rapide pour AKAP12 anticorps (ABIN306674)

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AKAP12 anticorps

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blot (2-5 ug/ml), immunohistochemistry and immunoprecipitation. Positive Control: Rat aortic smooth muscle.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Stock: -20 °C

Détails sur AKAP12

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Autre désignation: SSeCKS - myristylated (PKC) substrate

Sujet: Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicatedduring the process of spermiogenesis and in the actin-based stellate morphology of mesangial cellsSynonyms: SSeCKS, A-kinase anchor protein 12, AKAP12, src-suppressed C kinase substrate.

UniProt: Q62766

Pathways: cAMP Metabolic Process