PTGER2 anticorps

N° du produit ABIN306864

Détail du produit anti-PTGER2 anticorps

Antigène: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTGER2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Boeuf (Vache), Humain, Rat

Attributs du produit: Prostaglandin E2 Receptor Subtype EP2, Provided under license from Allergan, Inc. United States Patent No. 5,716,835,Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.

Purification: Protein A/G Chromatography

Immunogène: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP2 receptor protein and mouse myeloma cells.

Clone: 3E6

Isotype: IgG1

Information d'application

Indications d'application: This antibody can be used for Western blot analysis (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur PTGER2

Antigène: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Autre désignation: Prostaglandin-E2 receptor EP2 (PTGER2 Produits)

Synonymes: anticorps EP2, anticorps Ptgerep2, anticorps ptger2, anticorps ptger2l, anticorps zgc:63974, anticorps MGC69060, anticorps PTGER2, anticorps Ptger-ep2, anticorps si:ch211-13n20.1, anticorps si:dkey-29m11.3, anticorps zgc:136608, anticorps prostaglandin E receptor 2, anticorps prostaglandin E receptor 2 (subtype EP2), anticorps prostaglandin E receptor 2a (subtype EP2), anticorps prostaglandin E receptor 2 S homeolog, anticorps prostaglandin E receptor 2b (subtype EP2), anticorps PTGER2, anticorps Ptger2, anticorps ptger2a, anticorps ptger2.S, anticorps ptger2b

UniProt: Q62928