CD11b anticorps (FITC)

N° du produit ABIN316736

L’anticorps Souris Monoclonal anti-CD11b a été validé pour FACS. Il convient pour détecter CD11b dans des échantillons de Boeuf (Vache), Chévre et Mouton.

Aperçu rapide pour CD11b anticorps (FITC) (ABIN316736)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Boeuf (Vache), Chévre, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: CC126

Détail du produit anti-CD11b anticorps (FITC)

Specificité: This antibody recognises the CD11b cell surface antigen.

Attributs du produit: Synonyms: Integrin alpha-M, CR3A, MAC-1, MAC1, CR-3 alpha chain, Cell surface glycoprotein MAC-1subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11antigen-like family member B

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: 1/10, use 10 μL of the suggested working dilution to label 10^6 cells in100l.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Contains 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.

Date de péremption: 12 months

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b

Sujet: CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8 % spleen cells, 44 % bone marrow cells and less than 1 % of thymocytes and is commonly used as a microglial marker in nervous tissue.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

ID gène: 443217

UniProt: A2TJJ2

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation