LILRB1 anticorps

N° du produit ABIN316937

Détail du produit anti-LILRB1 anticorps

Antigène: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LILRB1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody is specific for CD85j, a member of the leukocyte immunoglobulin-like receptor (LIR) family.

Attributs du produit: Synonyms: LIR-3, ILT5, LIR3, HL9, Leukocyte immunoglobulin-like receptor subfamily B member 3,Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyteinhibitory receptor HL9, CD85 antigen-like family member A

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Monocyte derived dendritic cells

Clone: 4F9

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/50 - 1/200. Immunohistochemistry on frozen sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Date de péremption: 12 months

Détails sur LILRB1

Antigène: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Autre désignation: CD85j / LILRB1 (LILRB1 Produits)

Synonymes: anticorps CD85J, anticorps ILT-2, anticorps ILT2, anticorps LIR-1, anticorps LIR1, anticorps MIR-7, anticorps MIR7, anticorps leukocyte immunoglobulin like receptor B1, anticorps LILRB1

Sujet: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. CD85j is a receptor for MHC Class I molecules and ligand binding results in inhibitory signals and down-regulation of the immune response.CD85j is expressed predominantly on B-cells and monocytes, and at lower levels on dendritic cells, T-cells and natural killer (NK) cells.Synonyms: CD85 antigen-like family member J, ILT-2, ILT2, Immunoglobulin-like transcript 2, LILR-B1, LIR-1, LIR1, Leukocyte immunoglobulin-like receptor 1, Leukocyte immunoglobulin-like receptor subfamily B member 1, MIR-7, MIR7, Monocyte/macrophage immunoglobulin-like receptor 7

ID gène: 10859

UniProt: O75022

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response