GFRA4 anticorps

N° du produit ABIN317910

Détail du produit anti-GFRA4 anticorps

Antigène: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA4 est non-conjugé

Application: Western Blotting (WB)

Specificité: GFRα-4 antibody detects endogenous levels of GFRα-4 protein.(region surrounding Pro178)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GFRA4

Antigène: GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))

Autre désignation: GFRA4 / GDNFR-alpha 4 (GFRA4 Produits)

Synonymes: anticorps zgc:171814, anticorps AW060733, anticorps G630015H18Rik, anticorps GDNF family receptor alpha 4, anticorps GDNF family receptor alpha 4a, anticorps glial cell line derived neurotrophic factor family receptor alpha 4, anticorps GFRA4, anticorps gfra4a, anticorps Gfra4

Sujet: Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. Receptors for these factors include GFRα-1 (previously designated GDNFR-α), GFRα-2 (also designated RETL2), GFRα-3 and GFRα-4 (also known as persephin receptor). The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosylphosphoinositol linkage. Binding of GDNF or NTN to one of these receptors leads to the activation of the tyrosine kinase Ret. GFRα-4 mediates the activation and GDNF-induced autophosphorylation of the RET receptor. It is mainly expressed in the adult thyroid gland, but lower levels may also be detected in fetal adrenal and thyroid glands.Synonyms: GDNF family receptor alpha-4, GDNF receptor alpha-4, GFR-alpha-4, Persephin receptor

Poids moléculaire: approx. 30 kDa

ID gène: 64096

NCBI Accession: NP_071422

UniProt: Q9GZZ7