ASK1 anticorps (C-Term)
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- Antigène Voir toutes ASK1 (MAP3K5) Anticorps
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ASK1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody recognises ASK1 (Apoptosis signal-regulating kinase 1) a 155 kDa protein belonging to the protein kinase superfamily.
- Purification
- Purified
- Immunogène
- A peptide corresponding to amino acids near the carboxy terminus of human ASK1.
- Isotype
- IgG
- Top Product
- Discover our top product MAP3K5 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 155 kDa in SW1353 celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
- Autre désignation
- MEKK5 / ASK1 (MAP3K5 Produits)
- Synonymes
- anticorps ASK1, anticorps MAPKKK5, anticorps MEKK5, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MUD21.11, anticorps MUD21_11, anticorps 7420452D20Rik, anticorps ASK, anticorps Mekk5, anticorps Ask1, anticorps RGD1306565, anticorps mitogen-activated protein kinase kinase kinase 5, anticorps MAP3K5, anticorps MAPKKK5, anticorps Map3k5, anticorps map3k5
- Sujet
- ASK1 is a serine/threonine kinase, also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis. ASK1 is widely expressed in a variety of human tissues including the heart and pancreas.Synonyms: Apoptosis signal-regulating kinase 1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, Mitogen-activated protein kinase kinase kinase 5
- ID gène
- 4217
- NCBI Accession
- NP_005914
- UniProt
- Q99683
- Pathways
- Signalisation MAPK, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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