This antibody recognizes the Human CD32 antigen. Clone AT10 blocks the binding of IgG to Fc gamma R11 (See Larsson, M. et al. for details). SM1092LE is recommended for this purpose.
Purification
Affinity chromatography on Protein A
Immunogène
K562 cell line. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
anticorps CD32, anticorps CD32A, anticorps CDw32, anticorps FCG2, anticorps FCGR2, anticorps FCGR2A1, anticorps FcGR, anticorps IGFR2, anticorps CD32a, anticorps Fc fragment of IgG receptor IIa, anticorps FCGR2A
Sujet
CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation.CD32 is expressed by B cells, monocytes, granulocytes and platelets.Synonyms: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II