CD14 anticorps (AA 39-41, AA 43-44)
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- Antigène Voir toutes CD14 Anticorps
- CD14
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Épitope
- AA 39-41, AA 43-44
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD14 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificité
- Soluble and membrane bound human CD14 The antibody blocks LPS binding to membrane bound CD14
- Réactivité croisée
- Corynebacterium diphtheriae, Boeuf (Vache), Chien, Cobaye, Cheval, Porc
- Réactivité croisée (Details)
- cattle++, swine ++, dog+ horse+, guinea pig +,Inhibits binding of LPS to CD14 of swine++, dog+, cattle +, dog+, more than titer 10.000.
- Purification
- Protein A affinity column
- Immunogène
- Monocytes of different species and immunoaffinity purified soluble human CD14
- Clone
- BiG14
- Isotype
- IgG1
- Top Product
- Discover our top product CD14 Anticorps primaire
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- Indications d'application
- binding titre at human CD14 transfected CHO-cells: 1:50.000
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with bidistilled water
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.6
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
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Endothelin receptor antagonists attenuate the inflammatory response of human pulmonary vascular smooth muscle cells to bacterial endotoxin." dans: The Journal of pharmacology and experimental therapeutics, (2013) (PubMed).
: "Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood." dans: Medical microbiology and immunology, Vol. 201, Issue 3, pp. 327-35, (2012) (PubMed).
: "Influence of serum on the immune recognition of a synthetic lipopeptide mimetic of the 19-kDa lipoprotein from Mycobacterium tuberculosis." dans: Innate immunity, (2009) (PubMed).
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Endothelin receptor antagonists attenuate the inflammatory response of human pulmonary vascular smooth muscle cells to bacterial endotoxin." dans: The Journal of pharmacology and experimental therapeutics, (2013) (PubMed).
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- Antigène
- CD14
- Autre désignation
- CD14 (CD14 Produits)
- Synonymes
- anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
- Sujet
- Background: biG 14 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
- Poids moléculaire
- ~50kDa
- ID gène
- 929
- NCBI Accession
- NP_000582
- UniProt
- P08571
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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