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CD14 anticorps (AA 33-44)

CD14 Reactivité: Humain FACS, Agon Hôte: Souris Monoclonal biG4 unconjugated
N° du produit ABIN343171
  • Antigène Voir toutes CD14 Anticorps
    CD14
    Épitope
    • 16
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-44
    Reactivité
    • 268
    • 55
    • 32
    • 30
    • 29
    • 28
    • 25
    • 24
    • 24
    • 18
    • 17
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 224
    • 64
    • 25
    • 3
    • 1
    Souris
    Clonalité
    • 253
    • 64
    Monoclonal
    Conjugué
    • 128
    • 30
    • 24
    • 18
    • 15
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD14 est non-conjugé
    Application
    • 223
    • 104
    • 64
    • 59
    • 54
    • 50
    • 22
    • 22
    • 21
    • 14
    • 14
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Agonist (Agon)
    Specificité
    Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.
    Purification
    Protein A affinity column
    Immunogène
    human Monocytes
    Clone
    BiG4
    Isotype
    IgG2a
    Top Product
    Discover our top product CD14 Anticorps primaire
  • Indications d'application
    no significant inhibition of LPS binding to CD14
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with bidistilled water
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.8
    Agent conservateur
    Without preservative
    Stock
    -20 °C,-80 °C
  • Antigène
    CD14
    Autre désignation
    CD14 (CD14 Produits)
    Synonymes
    anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
    Sujet
    Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    Poids moléculaire
    ~50kDa
    ID gène
    929
    NCBI Accession
    NP_000582
    UniProt
    P08571
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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